BMS 8 | TargetMol

カタログ番号	製品名	別名	ターゲット
T26859	BMS-8		PD-1/PD-L1
	BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.		PD-1/PD-L1
T30531L	BMS-561392 Formic acid	BMS-561392 Formic acid(611227-74-8 Free base)	MMP
	BMS-561392 Formic acid is a selective inhibitor of TACE and reduces TNFalpha levels.		MMP
T10962	Dasatinib-d8	BMS-354825 D8	Others
	Dasatinib D8 is deuterium-labeled dasatinib. Dasatinib is a dual Bcr-Abl and Src family tyrosine kinase inhibitor.		Others
T71972	N-Fmoc-8-aminooctanoic acid
	N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. N-Fmoc-8-aminooctanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be ...
T4598	BMS-5	BMS5,LIMKi 3	LIM Kinase
	BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.		LIM Kinase
T5398	BMS 599626 2HCl (873837-23-1(HCl))	AC480 dihydrochloride	HER
	BMS 599626 2HCl (873837-23-1(HCl)) (AC480 dihydrochloride) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100-fold to Lck, VEGFR2, c-Kit, MET, etc.		HER
T2545	Lomitapide Mesylate	BMS-201038 mesylate,AEGR-733 mesylate	CETP
	Lomitapide Mesylate (BMS-201038 mesylate) is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.		CETP
T3146	BMS-202	PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2	Apoptosis , PD-1/PD-L1
	BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.		Apoptosis , PD-1/PD-L1

Compounds

BMS-8

T26859

Synonym:

Target: PD-1/PD-L1

BMS-561392 Formic acid

T30531L

Synonym: BMS-561392 Formic acid(611227-74-8 Free base)

Target: MMP

Dasatinib-d8

T10962

Synonym: BMS-354825 D8

Target: Others

N-Fmoc-8-aminooctanoic acid

BMS-5

Synonym: BMS5,LIMKi 3

Target: LIM Kinase

BMS 599626 2HCl (873837-23-1(HCl))

T5398

Synonym: AC480 dihydrochloride

Target: HER

Lomitapide Mesylate

T2545

Synonym: BMS-201038 mesylate,AEGR-733 mesylate

Target: CETP

BMS-202

T3146

Synonym: PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2

Target: Apoptosis, PD-1/PD-L1

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04123	CEACAM1 Protein, Human, Recombinant (His & hFc)	Human	HEK293
	The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and diffe...
TMPY-00668	APP/Protease nexin-II Protein, Human, Recombinant (hFc)	Human	HEK293
	Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPJ-00828	Tau-F Protein, Human, Recombinant	Human	E. coli
	Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons...
TMPJ-00808	CD45RA Protein, Human, Recombinant (His)	Human	Human Cells
	Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a var...
TMPY-06707	Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His)	Human	HEK293
	Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr...
TMPJ-01330	CD299 Protein, Human, Recombinant (His & Flag)	Human	Human Cells
	CD299 is also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called neck domain, mediates oligermerization. Multiple human DC-S...
TMPY-00717	CEACAM1 Protein, Human, Recombinant (His)	Human	HEK293
	The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and diffe...
TMPH-01705	Mucin-1/MUC1 Protein, Human, Recombinant (His)	Human	E. coli
	Mucin-1/MUC1 Protein, Human, Recombinant (His) is expressed in E. coli with N-terminal 6xHis tag. The predicted molecular weight is 31.2 kDa. Accession number: P15941-8